With the continuous deepening of digital transformation, manufacturing enterprises have put forward higher requirements for production collaboration, real-time response and fine control. Focusing on the construction and implementation path of the digital factory under the framework of high efficiency industrial automation system integration, this paper constructs an overall method covering target decomposition, system architecture design, multi-level data integration, collaborative control of industrial Internet and edge computing, digital twin and intelligent analysis and optimization, and phased promotion. In the verification of a discrete manufacturing workshop, 68 key devices and 214 sensing acquisition points are connected to the system. The success rate of device access is 98.6%, the average response time delay is 0.75 s, the success rate of scheduling is 96.0%, the first pass rate of products is increased to 97.1%, and the energy consumption per unit output value is reduced by 18.3%. The research shows that the path can enhance the ability of factory data penetration, business interaction and continuous optimization, and has practical reference significance for the digital upgrading of manufacturing enterprises.