Intelligent agriculture, as a composite specialty integrating multiple disciplines and multiple technologies, is facing a large talent gap. This paper takes the applied agriculture-related higher vocational colleges and universities as a research sample, and integrates the concept of aesthetic education into the innovation mechanism of talent cultivation mode. In terms of teaching technology and tools, three-dimensional virtual technology is used to build a simulation teaching and training scene in agriculture-related higher vocational colleges, constructing a virtual plant model and a virtual animal model respectively. The scene uses binocular stereo vision measurement to obtain the 3D coordinate data of the required objects, and uses the ICP algorithm to carry out the point cloud fine alignment of the data, thus realizing the 3D data modeling of the objects. In terms of teaching design, a “garden-school linkage” talent cultivation path is proposed under the concept of aesthetic education. In the teaching application of the comprehensive virtual simulation teaching platform and the concept of aesthetic education, the students in the experimental group improved their agricultural theory level between 0.4063~2.125 in each achievement interval, and their agricultural practice level had a significant difference with that of the preexperimental level (p=0.035), and more than half of the students had a positive intention to participate in and interest in this cultivation mechanism.