There are problems in the optimization design of grouting reinforcement technology parameters for high-altitude high-pressure water rich tunnels, such as the selection of grouting materials, grouting pressure, layout of grouting holes, and control of grouting volume. This article studies the optimization design theory of grouting reinforcement technology parameters in the construction of high-altitude high-pressure water rich tunnels. Taking a water rich section of a tunnel as the research object, the ABAQUS finite element analysis software is used to numerically simulate the curtain grouting process. By comparing the data characteristics under two different working conditions, the regulating effect of grouting reinforcement layer on water inflow rate was explored, and the grouting technical parameters were optimized and adjusted based on simulation results. Experimental data shows that compressing the grouting range to within 4 meters can not only ensure that the permeability ratio meets technical requirements, but also significantly reduce material consumption costs. On this basis, a practical and feasible implementation plan for curtain grouting was ultimately formulated. The research results can provide reference for the construction of deep buried, high-pressure, and water rich tunnels. This study will provide theoretical basis for the optimization design of grouting reinforcement technology parameters in the construction of high-altitude high-pressure water rich tunnels, and provide guidance for related engineering design, construction, and management work.