The grassroots organization of the party is the foundation of all the party’s work and fighting force. In this paper, the intelligent management system architecture driven by cloud computing platform is designed for the informatization needs of grassroots party organization construction. Methodologically, a theoretical model of intelligent party building containing intelligent perception, intelligent linkage, intelligent analysis and intelligent decision-making is constructed, the system framework is designed by adopting the cloud computing three-layer architecture and B/S architecture, the entropy weight method is applied to determine the weights of the evaluation indexes, and a fuzzy comprehensive judgment model is established to evaluate the system quality and efficiency. The results show that the application design has the highest weight of 31.65%, and the weights of the three indicators of management mechanism, operation and maintenance, and information management are 0.0976, 0.0838, and 0.0918, respectively; the comprehensive evaluation score of the system is 3.234, which is in the general to good level; compared with the big data platform, the CPU and memory utilization rate of the cloud computing platform is significantly reduced. The study shows that the system architecture is reasonable and effective, can meet the intelligent management needs of grassroots party organizations, and provides a feasible solution for the transformation of party building work informationization.