In this paper, we designed a randomized controlled experiment to include adult volunteers with defecation problems, and compare the degree of improvement of the digestive system and changes in intestinal flora between the dietary strategy intervention group and the blank control group over a 5-week period. Immunity function experiments were carried out using immunocompromised model mice and normal mice, which were given low, medium and high doses of dietary strategies and normal feed feeding, respectively, and the immunity function indexes were detected after 5 weeks of intervention. The results showed that the subjects in the intervention group showed significant improvement in several indexes, i.e., the dietary strategy could effectively improve human intestinal health. The high-dose dietary strategy significantly increased ConA-induced lymphocyte transformation rate and NK cell activity in immunosuppressed mice, and enhanced DTH and HC50 levels in normal mice. Combining the results of the two parts, it is hypothesized that the dietary strategy promotes beneficial bacterial colonization and metabolism by remodeling the intestinal microbial environment, which in turn modulates the host immune system.
