Against the backdrop of the Internet era, international cultural communication plays a vital role in strengthening national cultural soft power, and the key to such communication lies in the competence of international cultural communication talents. This paper uses structural equation modeling and exploratory factor analysis to explore the influencing factors of the cultivation of Chinese cultural international communication talents, and then uses a system dynamics model to analyze the operation mechanism of the cultivation of cultural international communication talents. On this basis, a teaching mode for the cultivation of cultural communication ability of international communication talents is proposed and applied to teaching practice. The study shows that the synergy mechanism between discipline and specialty exerts a significantly positive effect on talent cultivation performance, while the intensity of industry-university cooperation research has a significant inverted U-shaped moderating effect between the two. Government guidance, rational allocation of elements and multi-channel fund-raising are the main motivating factors driving the integration of industry and academia in cultivating international communication talents for Chinese culture. In addition, the integration of international communication talents cultivation pathway into the teaching mode can more effectively improve students’ learning motivation, and the experimental group using this teaching mode effectively improved their intercultural communication skills compared with the control group using the conventional mode (p < 0.05).