This research integrates data mining techniques into the transformation of university physical education programs, creating and executing a physical education course configuration system based on data mining techniques. This study suggests solutions for transforming university physical education programs, as well as solutions for promoting the physical and mental development and athletic skills of the learners. This study evaluates the success of the course configuration system and solutions suggested above from two angles: learners’ physical and mental development and athletic skills acquisition. From the experimental results, it can be seen that there are remarkable differences between the experimental group and the control group, who have comparable pre-experimental conditions. With regard to the physical and mental development results, the scores of the experimental group were 4.99 to 10.89 higher than those of the control group, where all P-values were less than 0.01 and showed statistically significant differences. In terms of athletic skills acquisition, the experimental group obtained scores that exceeded those of the control group by 3.29 to 6.37 points.
