China has been experiencing a constant improvement in its economic structure and industrial structure with an upward trend in demand on innovative and specialized talents. This leads to greater demands on innovation and entrepreneurship education. In light of the inevitability of the integrated approach of industries and education to train talents, the present paper develops the model of talent training of innovation and entrepreneurship, which embodies the concept of the integration of industries and education. In line with the CIPP assessment model, index system is developed to assess the quality of innovation and entrepreneurship education. The weight of each index is calculated based on the entropy weight method and the cloud model is applied to assess the quality of innovation and entrepreneurship education in colleges and universities overall. The subjects of the teaching experiment were undergraduate students who majored in civil engineering. The findings indicated that the experimental group scored 62.16 + 3.59 points in terms of innovation and entrepreneurship awareness, which was 76.49 percent higher than the control (blank) group and the difference between the two groups was significant (P < 0.05). Based on the cloud model, the evaluation grade of the quality of innovation and entrepreneurship education in higher education is defined as good. It implies that we should enhance the curriculum system as well as increase teaching staff and distribute the available resources properly to achieve the best possible implementation of the concept of industry-education in higher education on the aspect of innovation and entrepreneurship education in colleges and universities.