Colleges and universities should focus on cultivating students’ comprehensive ability when teaching, not only focusing on the improvement of students’ professional ability, but also paying more attention to students’ mental health. This paper takes the general education course of mental health education, the activity course of mental health education, and the comprehensive course of mental health education as the entry point to construct the campus psychological course system under the perspective of positive psychology. Immediately after that, according to the principle of evaluation index selection, the evaluation indexes of campus psychological course system under positive psychology perspective are determined, followed by the entropy weight method to calculate the evaluation index weights of campus psychological course system under positive psychology perspective, and the weight values are substituted into the cloud model as inputs, so that the comprehensive evaluation values of campus psychological course system under positive psychology perspective can be calculated. The comprehensive evaluation cloud of campus psychology course system is between “E” [40, 60) and “F” [60, 80), and the numerical values are obviously biased toward the left endpoint of the interval [40, 60) and part of the values fall into the interval [50, 60), which indicates that the positive psychology program system from the perspective of positive psychology has been evaluated. Psychology perspective of the campus psychology program system is in the middle primary stage. This study not only promotes the self-growth of college students, but also helps students to establish a correct state of mental health.